Our main activities:
We are synthesizing materials for our customers from various fields of organic chemistry from g to kg scale. These materials are typically not available or they are very expensive at catalogue companies.
When a compound was prepared in the research lab in gram quantities and larger amounts are required, the next task is preparation of the material on 100 g scale. This amount must be produced without column chromatography. Sometimes the reaction sequence requires modification. The procedure will be the basis of the pilot plant scale-up experiments. We are fully equipped up to 10 L scale. In-lab GC, HPLC and NMR help us to find the way how to effectively prepare this amount.
Before scaling-up a lab procedure, reaction conditions should be optimised. The optimisation goals may be
- minimum cost with maximum yield,
- scalable robust procedure,
- minimizing environmental impact, safety considerations,
- appropriate combination of all of these.
This type of work requires certain lab experience, some industrial point of view, efficient experimental design, good analytical and chromatography background. We can use routinely in-lab GC and HPLC not only for product analyses but monitoring reactions.
As our company name suggests, we enjoy working on quite different fields of organic chemistry. However, in the last 3 years we were involved in a significant carbohydrate chemistry project: industrialisation of a biologically active oligosacharide. Working on this project made us experienced in carbohydrate chemistry.